occurrenceID	taxonID	catalogNumber	collectionCode	institutionCode	typeStatus	verbatimLabel	sex	individualCount	eventDate	recordedBy	recordNumber	decimalLatitude	decimalLongitude	minimumElevationInMeters	maximumElevationInMeters	minimumDepthInMeters	maximumDepthInMeters	country	stateProvince	municipality	locality	references	associatedOccurrences	associatedReferences	associatedSequences	basisOfRecord	eventRemarks	occurrenceRemarks
03E4D873FFFEDC5DFFDBB4D9BC881F89.mc.3B256338FFFDDC5DFF3AB7C0BC841F89	03E4D873FFFEDC5DFFDBB4D9BC881F89.taxon			I		Interestingly, since hypertension is a common complication of type 2 diabetes mellitus, dihydrotanshinone I has been proposed as a substance with both anti-hypertensive activity, due to mineralocorticoid receptor antagonism, and antihyperglycemic effects (Liu et al., 2010). Diabetes-induced vascular dysfunction are attenuated by rosmarinic acid, which acts as a vasoactive substance and a cardioprotector through its antioxidant property (Karthik et al., 2011; Sotnikova et al., 2013; Javidanpour et al., 2017)		1														https://treatment.plazi.org/id/03E4D873FFFEDC5DFFDBB4D9BC881F89#3B256338FFFDDC5DFF3AB7C0BC841F89				MaterialCitation		
03E4D873FFFDDC5CFC8DB462BF631C4E.mc.3B256338FFFDDC5CFC23B7C0BF7F1C4E	03E4D873FFFDDC5CFC8DB462BF631C4E.taxon			NO		experiments on guinea pig isolated tissues showed that the decoction of ginger possesses weak negative inotropic and chronotropic intrinsic activities, along with a significant intrinsic relaxant activity on smooth muscle with a greater potency on ileum than on aorta. The study on the main pure components supports the relationship between 6 - and 8 - gingerol and 6 - shogaol and these effects. These results are in agreement with the activity of calcium channel modulators, which influence more strongly the not vascular muscles than vascular one (Leoni et al., 2017). Previous researches had evidenced, for 6 -, 8 - and 10 - gingerol and, to a minor extent, also for 6 - shogaol (Fig. 13), a vasodilator effect through a combination of NO releasing and calcium antagonist mechanism (Ghayur et al., 2005). More recently, 6 - gingerol has been shown to attenuate the increased level of blood glucose and to improve cardiac hemodynamics in diabetic rats (El-Bassossy et al., 2016) and it has been identified as a novel angiotensin II type 1 receptor antagonist (Liu et al., 2013). Inhibition of TGF-β- stimulated biglycan synthesis by 6 - gingerol suggests the potential role of ginger in the prevention of atherosclerosis (Kamato et al., 2013)		1														https://treatment.plazi.org/id/03E4D873FFFDDC5CFC8DB462BF631C4E#3B256338FFFDDC5CFC23B7C0BF7F1C4E				MaterialCitation		
